Synergistic effects on gene delivery – co-formulation of small disulfide-linked dendritic polycations with Lipofectamine 2000™
نویسندگان
چکیده
منابع مشابه
Synergistic effects on gene delivery--co-formulation of small disulfide-linked dendritic polycations with Lipofectamine 2000.
This paper describes the application of gene delivery vectors based on connecting together two well-defined low-generation poly(L-lysine) (PLL) dendrons using a disulfide-containing linker unit. We report that the transfection ability of these vectors in their own right is relatively low, because the low-generation number limits the endosomal buffering capacity. Importantly, however, we demonst...
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ژورنال
عنوان ژورنال: Organic & Biomolecular Chemistry
سال: 2009
ISSN: 1477-0520,1477-0539
DOI: 10.1039/b818469k